Abstract
Prophylactic injection of the natural antioxidant alpha-tocopherol and synthetic antioxidants ionol, diludin and 6-mercurascan prevented the development of lesions during acute renal ischemia and subsequent reperfusion. Ionol proved more effective on intraperitoneal injection than on intragastric route of administration. It has been demonstrated that antiischemic effect of ionol is related to its ability to exhibit the process of lipid peroxidation.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Animals
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Antioxidants / therapeutic use*
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Butylated Hydroxytoluene / therapeutic use
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Dicarbethoxydihydrocollidine / analogs & derivatives
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Dicarbethoxydihydrocollidine / therapeutic use
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Fluoresceins / therapeutic use
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Ischemia / drug therapy*
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Kidney / blood supply*
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Male
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Organomercury Compounds / therapeutic use
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Rats
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Vitamin E / therapeutic use
Substances
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Antioxidants
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Fluoresceins
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Organomercury Compounds
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etidin
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Vitamin E
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Butylated Hydroxytoluene
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mercurascan
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Dicarbethoxydihydrocollidine