The results of combined treatment were analysed in 38 cases of cerebral gliomas. In the group of 14 patients with glioblastoma multiforme treated surgically and by later radiotherapy and chemotherapy by the schedule of Hildebrand a mean arrival time of 116 weeks was obtained and the one-year survival rate was 71%. In the group of inoperable gliomas (16 cases) treated by radiotherapy and chemotherapy the mean survival time was 47 weeks and the one-year survival rate was 44%.