Myxopapillary ependymoma of the filum terminale and cauda equina in childhood: report of seven cases and review of the literature

Neurosurgery. 1984 Feb;14(2):204-10. doi: 10.1227/00006123-198402000-00015.

Abstract

Seven of fourteen children with spinal cord ependymoma had myxopapillary tumors of the filum terminale. These tumors made up 15.9% of all primary spinal neuroectodermal tumors in children (44 cases) seen during a 62-year period (1919 to 1981). Their clinical presentation, radiological features, pathological findings, treatment, and outcome are reported. Six of the seven patients were known to be alive at the time of writing. The seventh patient was lost to follow-up after 3 years without tumor recurrence. Of 5 patients whose primary mode of treatment was operation alone. 3 had intraspinal or intracranial recurrences. Despite tumor recurrences, 2 patients were long term survivors after further operation and irradiation, whereas the third patient recently received craniospinal irradiation for intracranial tumor recurrence. The 2 patients who did not have tumor recurrence after operation alone had been followed for 3 and 7 years, respectively. Two children with subtotal tumor resection and spinal irradiation had no recurrences at 1 and 17 years, respectively. Our data suggest that this unusual subtype of spinal ependymoma is not uncommon during childhood and has a good prognosis. All patients with this tumor require prolonged follow-up for tumor recurrence after operation and irradiation.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Cauda Equina / diagnostic imaging*
  • Cauda Equina / pathology
  • Child
  • Ependymoma / diagnostic imaging*
  • Ependymoma / pathology
  • Female
  • Humans
  • Male
  • Myelography
  • Peripheral Nervous System Neoplasms / diagnostic imaging*
  • Peripheral Nervous System Neoplasms / pathology
  • Pneumoencephalography
  • Tomography, X-Ray Computed