[Hemodynamic effects of 2 different doses of midazolam in combination with fentanyl for induction of anesthesia in surgery of the abdominal aorta]

Ann Fr Anesth Reanim. 1984;3(3):168-70. doi: 10.1016/s0750-7658(84)80047-7.
[Article in French]

Abstract

The haemodynamic effects of anaesthetic induction with midazolam, fentanyl and pancuronium bromide were studied in two groups of patients undergoing abdominal aortic surgery: group A (10 patients receiving 0.2 mg X kg-1 midazolam) and group B (9 patients receiving 0.3 mg X kg-1 midazolam). Haemodynamic parameters were measured before induction after fluid loading and 15 min after induction. Heart rate, mean right atrial pressure, systemic and pulmonary vascular resistances, mean pulmonary wedge pressure and right ventricular stroke work index remained steady. On the other hand, mean arterial and pulmonary arterial pressures, systolic, cardiac and left ventricular stroke work indices fell significantly in both groups. However there was no statistically significant difference between the two groups.

Publication types

  • English Abstract

MeSH terms

  • Anesthesia, General*
  • Anesthetics / administration & dosage*
  • Aorta, Abdominal / surgery*
  • Benzodiazepines / administration & dosage*
  • Drug Combinations
  • Fentanyl / administration & dosage*
  • Hemodynamics / drug effects
  • Humans
  • Midazolam

Substances

  • Anesthetics
  • Drug Combinations
  • Benzodiazepines
  • Midazolam
  • Fentanyl