Abstract
In vitro susceptibilities of 87 isolates of non-penicillinase-producing Neisseria gonorrhoeae and 8 isolates of penicillinase-producing N. gonorrhoeae to Ro 13-9904, cefuroxime, cefoxitin, and ampicillin were determined. Ro 13-9904 was the most effective of the four drugs, inhibiting growth of both non-penicillinase-producing and penicillinase-producing N. gonorrhoeae.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Ampicillin / pharmacology*
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Cefoxitin / pharmacology
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Ceftriaxone
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Cefuroxime / pharmacology
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Cephalosporins / pharmacology*
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Humans
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Microbial Sensitivity Tests
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Neisseria gonorrhoeae / drug effects*
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Neisseria gonorrhoeae / enzymology
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Penicillinase / biosynthesis
Substances
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Cephalosporins
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Cefoxitin
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Ceftriaxone
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Ampicillin
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Penicillinase
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Cefuroxime