Prognostic indicators of herpetic keratitis. Analysis of a five-year observation period after corneal ulceration

Arch Ophthalmol. 1981 Sep;99(9):1578-82. doi: 10.1001/archopht.1981.03930020452009.

Abstract

Clinical features of 152 patients with herpetic keratitis after a five-year observation period were analyzed. When compared with dendritic ulceration, geographic ulcers that had been symptomatically present for a longer time were more likely to have been treated with a topical steroid and took longer to heal. After treatment of the corneal ulceration, 40% of the patients experienced a recurrent herpetic ulcer, 25% experienced disciform or irregular stromal keratouveitis, 5% experienced ocular hypertension, and 6% had a decrease in visual acuity caused by corneal scarring. Recurrent ulcerative herpetic keratitis occurred more frequently in men and in patients who entered the study with a history or previous herpetic ulceration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antiviral Agents / therapeutic use
  • Child
  • Corneal Ulcer / etiology
  • Corneal Ulcer / therapy*
  • Debridement / methods
  • Female
  • Follow-Up Studies
  • Humans
  • Intraocular Pressure
  • Keratitis, Dendritic / therapy*
  • Male
  • Middle Aged
  • Prognosis
  • Random Allocation
  • Recurrence
  • Trifluridine
  • Vidarabine / therapeutic use
  • Visual Acuity

Substances

  • Antiviral Agents
  • Vidarabine
  • Trifluridine