Post-translation modification of xanthine dehydrogenase in a natural population of Drosophila melanogaster

Genetics. 1981 Aug;98(4):817-31. doi: 10.1093/genetics/98.4.817.

Abstract

Second chromosomes of D. melanogaster were isolated from a single natural population, and 40 were analyzed by gel-sieving electrophoresis for the presence of polymorphic loci on chromosome 2 that act to modify xanthine dehydrogenase and/or aldehyde oxidase, whose structural genes map to chromosome 3. Clear evidence of polymorphism for one or more xanthine dehydrogenase modifier loci was obtained.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aldehyde Oxidoreductases / genetics
  • Animals
  • Drosophila melanogaster / genetics*
  • Genes
  • Genetic Variation
  • Ketone Oxidoreductases / genetics*
  • Polymorphism, Genetic
  • Protein Biosynthesis
  • Protein Precursors / metabolism
  • Xanthine Dehydrogenase / genetics*

Substances

  • Protein Precursors
  • Xanthine Dehydrogenase
  • Aldehyde Oxidoreductases
  • Ketone Oxidoreductases