A 'new' allele giving further insight into the LW blood group system

Vox Sang. 1982;42(5):252-5. doi: 10.1111/j.1423-0410.1982.tb00753.x.

Abstract

Nea, a red cell antigen present in 6% of Finnish people but in less than 1% of other Europeans tested, is shown to be part of the LW system. Tests on 10,025 Finnish donors show the antithetical relationship of anti-Nea (proposed name anti-LWb) and anti-LW made by LW3 people (proposed name anti-LWa). Tests on families of previously reported LW3 propositi and of LW(a-b+) Finnish donors support the hypothesis that Nea (LWb) is an allele at the LW locus which when homozygous produces the phenotype once called LW3.

MeSH terms

  • Alleles*
  • Antigen-Antibody Reactions
  • Female
  • Gene Frequency
  • Humans
  • Infant, Newborn
  • Male
  • Rh-Hr Blood-Group System / genetics*

Substances

  • Rh-Hr Blood-Group System