Abstract
Thirty-two patients with by non oat cell bronchogenic carcinoma were admitted to a protocol including Cyclophosphamide (CTX) 1,000 mg/m2 i.v. day 1, VP16-213 200 mg/m2 p.o. day 1-3, every 3 weeks. Partial remissions were seen in 2 of 27 evaluable patients; 16 of 27 showed no change. Mean survival was 36.4 weeks, median survival was 38 weeks.
MeSH terms
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Carcinoma, Bronchogenic / drug therapy*
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Cyclophosphamide / adverse effects
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Cyclophosphamide / therapeutic use*
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Drug Therapy, Combination
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Etoposide / adverse effects
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Etoposide / therapeutic use*
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Female
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Humans
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Lung Neoplasms / drug therapy*
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Male
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Podophyllotoxin / analogs & derivatives*
Substances
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Etoposide
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Cyclophosphamide
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Podophyllotoxin