A study of the fate of gum karaya in the rat

Toxicol Lett. 1982 Oct;13(3-4):247-51. doi: 10.1016/0378-4274(82)90219-3.

Abstract

Rats were fed a diet containing 5% gum karaya for 24 h and faeces and urine were collected over 72 h. Faeces were examined, after methanolysis, by gas chromatography--mass spectometry and the quantity and monosaccharide composition of the faecal polysaccharide were compared with the dose and original composition of the gum polysaccharide. Gum-derived rhamnose was not found in the urine. Indications of minor quantitative changes in composition but no evidence of extensive degradation or absorption of gum polysaccharide, were found.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Diet
  • Feces / analysis
  • Karaya Gum / metabolism*
  • Male
  • Monosaccharides / analysis
  • Polysaccharides / analysis
  • Polysaccharides / metabolism*
  • Rats
  • Rats, Inbred Strains
  • Time Factors

Substances

  • Monosaccharides
  • Polysaccharides
  • Karaya Gum