The authors draw up "paludometric indications" by studying 938 children and youths, in the Kadiolo area, a humid savanna in the south of Mali, by the end of the dry season (beginning of March). These results give a global indication of 70.6% (cases of malaria) with 94.4% of P. falciparum and 9.96% cases of gametocytic indications. The numbers obtained far from the rainy season let us think that the annual transmission of malaria is continuous with a recrudescence in the humid season explaining largely the infantile mortality. The use of Nivaquine may easily protect these populations from the risk of malaria disease.