This is a report of two women who experienced radiation myelopathy 2,5 and 9 months after telecobalt radiation. Tetraplegia and paralysis of the inspiratory muscles developed rapidly in the first case whereas in the second case the paralysis and the initial Brown-Sequard syndrome improved after treatment with corticosteroids and infusion of Rheomacrodex and Sorbit. It should be stressed that in both cases the radiation stress on the spinal cord was under the limit of tolerance of 3300 to 4000 R. The differential diagnosis of radiation myelopathy from spinal metastasis is most important because the treatment is different for each conditions.