Cataractogenesis in the X-irradiated rabbit eye

Curr Eye Res. 1981;1(5):275-80. doi: 10.3109/02713688108999447.

Abstract

Studies were conducted on the development of cataract in the eyes of young (5-6 week old) New Zealand White rabbits exposed to 20 Gy of X-rays (1 Gy = 100 rads). The findings indicated that the opacities appear initially during the first week post-irradiation and follow a progression typical of cataract development in older rabbits and other species. However, advanced cataractous changes, as indicated by lens intumescence, occur concomitantly with complete opacification. They develop rapidly within a two day period between 2.5 to 3 months post-irradiation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cataract / etiology*
  • Lens, Crystalline / radiation effects*
  • Rabbits
  • Time Factors
  • X-Rays / adverse effects