Abnormal cardiovascular and electrocardiographic profiles and cardiac glycogen content in rabbits injected with scorpion venom

Indian J Physiol Pharmacol. 1981 Oct-Dec;25(4):351-5.

Abstract

Cardiovascular and ECG abnormalities were studied following injection of venom of Buthus tamulus, a common scorpion found in South India. Venom was administered in doses of 2 and 4 mg/kg body weight. Subsequent estimation of glycogen content of different chambers of the heart, showed a significant reduction in tissue glycogen levels in both atria and ventricles in animals treated with a venom dose of 2 mg/kg. However, a significant reduction occurred only in atria with a higher venom dose of 4 mg/kg.

MeSH terms

  • Animals
  • Dose-Response Relationship, Drug
  • Electrocardiography
  • Glycogen / analysis*
  • Heart / drug effects*
  • Myocardium / analysis*
  • Rabbits
  • Scorpion Venoms / administration & dosage
  • Scorpion Venoms / pharmacology*

Substances

  • Scorpion Venoms
  • Glycogen