Sixty-six infants aged 8 days to 3 months presented jaundice as a sign of urinary infection during a ten-year period 1968-1977. The main clinical and biochemical aspects are described. "E.coli" grew in 49 urine cultures (74.2%), but other bacteria were also found ("Klebsiella", "Proteus", "Pseudomonas", "A. aerogenes"). Hepatic function tests seem to prove that intrahepatic colostasis is the main mechanism involved, although hemolysis was also found in some cases. The importance of considering urinary infection in the diagnosis of jaundice during infancy is stressed.