Cardiotoxicity of 5-fluorouracil

Tumori. 1980 Oct 31;66(5):635-6. doi: 10.1177/030089168006600511.

Abstract

A case is reported of cardiotoxicity during a multiple drug treatment with fluorouracil, vincristine and CCNU in a patient with a large bowel cancer without any precedent history of heart disease. The patient had chest pain, with an altered ECG and increased serum levels of alpha HBDH.

Publication types

  • Case Reports

MeSH terms

  • Angina Pectoris / chemically induced*
  • Colonic Neoplasms / drug therapy
  • Drug Therapy, Combination
  • Female
  • Fluorouracil / administration & dosage
  • Fluorouracil / adverse effects*
  • Humans
  • Lomustine / administration & dosage
  • Middle Aged
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Lomustine
  • Fluorouracil