We present the clinical aspects and the evolution of 14 patients brought in the last 5 years in an ICU polyvalent with diagnostic of intoxication by organophosphate (OF) 10 and paraquat 4. The intoxicated by OF were subjugated at the same treatment record book with atropine, gastric washing, coal activated and pralidoxime. At the intoxicated by paraquat used precocious hemoperfusion. The mortality in intoxicated by OF went 20%, and 100% in paraquat intoxications. We analyzed to them the complications during their stay in ICU, as soon as diverse clinical aspects of this intoxications and equal form varied aspects about treatment.