Psychopathological dimensions in schizophrenia

Schizophr Bull. 1995;21(3):473-82. doi: 10.1093/schbul/21.3.473.

Abstract

To test underlying latent syndromes within schizophrenic syndromes assessed by the Positive and Negative Syndrome Scale (PANSS), a sample of 100 DSM-III-R schizophrenia patients was obtained through a semistructured interview for schizophrenia. Confirmatory factor analysis was used to evaluate the underlying symptomatological dimensions. The positive and negative construct was not confirmed by this study. The three- and four-dimension models obtained higher goodness of fit than the one- or two-dimension models. Models composed of three or four dimensions shared positive and negative syndromes, in addition to "disorder of relating" and/or "disorganization" dimensions. The disorder of relating dimension of PANSS was composed of emotional withdrawal and passive/apathetic social withdrawal. The disorganization dimension comprised two symptoms of PANSS (conceptual disorganization and poor attention) and an item not included in the PANSS: inappropriate affect. It is suggested that a schedule for the assessment of this item be added to the PANSS.

MeSH terms

  • Adolescent
  • Adult
  • Affective Symptoms / classification
  • Affective Symptoms / diagnosis
  • Affective Symptoms / psychology
  • Aged
  • Factor Analysis, Statistical
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Statistical
  • Patient Admission
  • Psychiatric Status Rating Scales / statistics & numerical data*
  • Psychometrics
  • Psychopathology
  • Schizophrenia / classification
  • Schizophrenia / diagnosis*
  • Schizophrenic Psychology*