Preoperative therapy for soft tissue sarcoma

Hematol Oncol Clin North Am. 1995 Aug;9(4):817-23.

Abstract

Soft tissue sarcomas appear to be an ideal tumor type for delivering preoperative therapy. The rationale for preoperative therapy is that it is delivered to undisturbed tissue planes with well-oxygenated tissue. This is of great benefit for radiation therapy, because with new computed tomography scan treatment planning it is possible to completely delineate the tumor without surgical clips or postoperative hematoma (or both) obscuring the tumor margin.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Chemotherapy, Adjuvant
  • Cisplatin / administration & dosage
  • Clinical Trials as Topic
  • Doxorubicin / administration & dosage
  • Humans
  • Ifosfamide / administration & dosage
  • Preoperative Care
  • Radiotherapy, Adjuvant
  • Sarcoma / mortality
  • Sarcoma / surgery
  • Sarcoma / therapy*
  • Soft Tissue Neoplasms / mortality
  • Soft Tissue Neoplasms / surgery
  • Soft Tissue Neoplasms / therapy*
  • Treatment Outcome

Substances

  • Doxorubicin
  • Cisplatin
  • Ifosfamide