Abstract
The synthesis and antimicrobial activity of some Mannich bases of diarylpyrroles are reported. The obtained data show that activity is closely connected to molecular basicity. Results are discussed on the basis of structure activity relationships.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents
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Anti-Infective Agents / chemical synthesis*
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / pharmacology
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Antifungal Agents / chemical synthesis*
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Antifungal Agents / chemistry
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Antifungal Agents / pharmacology
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Candida albicans / drug effects
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Gram-Negative Bacteria / drug effects
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Gram-Positive Bacteria / drug effects
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Pyrroles / chemical synthesis*
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Pyrroles / chemistry
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Pyrroles / pharmacology
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Structure-Activity Relationship
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents
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Antifungal Agents
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Pyrroles