There is some evidence from anglo-american clinical and experimental studies that gastro-esophageal reflux is more common in patients with laryngitis. Within the framework of an open study, 32 patients with reflux esophagitis and laryngitis were treated with 20 mg omeprazole daily. After 4 weeks at the latest, in all cases inflammation of the esophagus and larynx had healed completely and the patients were without complaints. Suggesting that reflux is the underlying etiology patients with laryngitis seem to benefit from omeprazole.