[Psychopharmacological study of two 3-arylsulfonyl 4-hydroxy-coumarines]

Ann Pharm Fr. 1995;53(5):215-9.
[Article in French]

Abstract

The pharmacological study of 3-(4-chlorophenylsulfonyl) 4-hydroxy-7-methoxy- coumarine and 3-(4-methylphenylsulfonyl) 4-hydroxy-7-methoxy-coumarine shows that these derivatives present low sedative effects on the central nervous system, particularly due to their actions upon temperature and motility, more accentuated for the chloro-substituted derivative.

Publication types

  • English Abstract

MeSH terms

  • 4-Hydroxycoumarins / pharmacology*
  • Animals
  • Behavior, Animal / drug effects
  • Coumarins / pharmacology
  • Drug Interactions
  • Male
  • Mice
  • Mice, Inbred Strains
  • Psychopharmacology
  • Psychotropic Drugs / pharmacology
  • Vitamin K / antagonists & inhibitors*
  • Vitamin K / pharmacology*

Substances

  • 4-Hydroxycoumarins
  • Coumarins
  • Psychotropic Drugs
  • Vitamin K
  • 4-hydroxycoumarin