Abstract
Anti-myeloperoxidase (MPO) antibodies are frequently encountered in patients with vasculitis. Using a competitive inhibition ELISA test and immunoblotting, we suggest that anti-MPO antibodies might represent a heterogenous group of auto-antibodies directed against different conformational epitopes of MPO molecule.
MeSH terms
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Antibodies, Antineutrophil Cytoplasmic
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Antibody Specificity
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Autoantibodies / blood*
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Autoantibodies / immunology
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Enzyme-Linked Immunosorbent Assay
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Epitopes / immunology
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Humans
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Immunoblotting
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Immunoglobulin G / blood
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Immunoglobulin G / immunology
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Peroxidase / immunology*
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Vasculitis / immunology*
Substances
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Antibodies, Antineutrophil Cytoplasmic
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Autoantibodies
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Epitopes
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Immunoglobulin G
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Peroxidase