In-vitro and in-vivo immunobiological properties of murine monoclonal anti-Brucella antibodies

R Adone; F Ciuchini; C Pistoia; G Piccininno

doi:10.1007/BF00173981

In-vitro and in-vivo immunobiological properties of murine monoclonal anti-Brucella antibodies

Appl Microbiol Biotechnol. 1994 Feb;40(6):818-21. doi: 10.1007/BF00173981.

Authors

R Adone¹, F Ciuchini, C Pistoia, G Piccininno

Affiliation

¹ Istituto Superiore di Sanità, Laboratorio di Medicina Veterinaria, Rome, Italy.

PMID: 7510505
DOI: 10.1007/BF00173981

Abstract

Features and protective activity of anti-Brucella murine monoclonal antibodies (Mabs) versus B. melitensis 16M were studied. All Mabs tested were able to confer a good passive protection and showed correlative biological properties in immunological reactions.

MeSH terms

Animals
Antibodies, Bacterial / administration & dosage
Antibodies, Bacterial / blood
Antibodies, Bacterial / immunology*
Antibodies, Monoclonal / administration & dosage
Antibodies, Monoclonal / blood
Antibodies, Monoclonal / immunology*
Antigens, Bacterial / immunology
Biotechnology
Brucella melitensis / immunology*
Brucella melitensis / isolation & purification
Brucellosis / immunology
Brucellosis / microbiology
Brucellosis / prevention & control
Cross Reactions
Epitopes / immunology
Immunization, Passive
Immunoglobulin Isotypes / immunology
In Vitro Techniques
Mice
Mice, Inbred BALB C
Spleen / microbiology

Substances

Antibodies, Bacterial
Antibodies, Monoclonal
Antigens, Bacterial
Epitopes
Immunoglobulin Isotypes