Detection of rotavirus in cerebrospinal fluid and blood of patients with convulsions and gastroenteritis by means of the reverse transcription polymerase chain reaction

S Nishimura; H Ushijima; S Nishimura; H Shiraishi; C Kanazawa; T Abe; K Kaneko; Y Fukuyama

doi:10.1016/0387-7604(93)90088-p

Detection of rotavirus in cerebrospinal fluid and blood of patients with convulsions and gastroenteritis by means of the reverse transcription polymerase chain reaction

Brain Dev. 1993 Nov-Dec;15(6):457-9. doi: 10.1016/0387-7604(93)90088-p.

Authors

S Nishimura¹, H Ushijima, S Nishimura, H Shiraishi, C Kanazawa, T Abe, K Kaneko, Y Fukuyama

Affiliation

¹ Department of Pediatrics, Teikyo University School of Medicine, Tokyo, Japan.

PMID: 7511877
DOI: 10.1016/0387-7604(93)90088-p

Abstract

Rotavirus RNA was detected in the blood and cerebrospinal fluid from eight Japanese children with convulsions and gastroenteritis in the acute stage by means of the reverse transcription polymerase chain reaction. This may suggest that rotavirus invades the central nervous system through blood vessels.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child, Preschool
Feces / chemistry
Feces / microbiology
Female
Gastroenteritis / blood
Gastroenteritis / cerebrospinal fluid
Gastroenteritis / microbiology*
Humans
Infant
Male
Polymerase Chain Reaction
RNA, Viral / analysis
RNA, Viral / blood
RNA, Viral / cerebrospinal fluid
RNA-Directed DNA Polymerase
Rotavirus / isolation & purification*
Rotavirus Infections / blood
Rotavirus Infections / cerebrospinal fluid
Rotavirus Infections / microbiology*
Seizures / blood
Seizures / cerebrospinal fluid
Seizures / microbiology*

Substances

RNA, Viral
RNA-Directed DNA Polymerase