A G-protein beta subunit that is expressed in the central nervous system of the mollusc Lymnaea stagnalis identified through cDNA cloning

J C Knol; E Roovers; E R van Kesteren; R J Planta; E Vreugdenhil; H van Heerikhuizen

doi:10.1016/0167-4889(94)90035-3

A G-protein beta subunit that is expressed in the central nervous system of the mollusc Lymnaea stagnalis identified through cDNA cloning

Biochim Biophys Acta. 1994 May 26;1222(1):129-33. doi: 10.1016/0167-4889(94)90035-3.

Authors

J C Knol¹, E Roovers, E R van Kesteren, R J Planta, E Vreugdenhil, H van Heerikhuizen

Affiliation

¹ Graduate School of Neurosciences Amsterdam, Research Institute Neurosciences Vrije Universiteit, Faculty of Chemistry, Department of Biochemistry and Molecular Biology, The Netherlands.

PMID: 7514444
DOI: 10.1016/0167-4889(94)90035-3

Abstract

We have cloned cDNA encoding a G-protein beta subunit from the central nervous system (CNS) of the mollusc Lymnaea stagnalis. The deduced protein is very homologous to other metazoan beta subunits. Thus, the Lymnaea CNS can be used as a model system to study beta gamma subunits in their native setting since its large neurons can be manipulated and studied relatively easily in vivo.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Base Sequence
Central Nervous System / chemistry*
DNA, Complementary / chemical synthesis
GTP-Binding Proteins / chemistry
GTP-Binding Proteins / genetics*
Lymnaea / genetics*
Lymnaea / ultrastructure
Molecular Sequence Data
RNA / isolation & purification
Sequence Alignment

Substances

DNA, Complementary
RNA
GTP-Binding Proteins

Associated data

GENBANK/Z23105