Abstract
Epstein-Barr virus (EBV) CD8+ cytotoxic T lymphocyte (CTL) epitopes are currently being considered for inclusion into subunit vaccines. Here we describe the characterization of five new CTL epitopes within EBV nuclear antigen 3 (EBNA3), confirming EBNA3 as a major target for CTL recognition.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Antigens, Viral / immunology*
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CD8 Antigens / immunology
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Callithrix
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Cell Line, Transformed
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Cell Nucleus / immunology
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DNA-Binding Proteins / immunology*
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Epitopes / analysis
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Epitopes / immunology*
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Epstein-Barr Virus Nuclear Antigens
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Herpesvirus 4, Human / immunology*
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Humans
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Lymphocyte Activation
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Molecular Sequence Data
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T-Lymphocytes, Cytotoxic / immunology*
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Vaccines, Synthetic / immunology*
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Viral Vaccines / immunology*
Substances
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Antigens, Viral
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CD8 Antigens
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DNA-Binding Proteins
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Epitopes
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Epstein-Barr Virus Nuclear Antigens
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Vaccines, Synthetic
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Viral Vaccines