Microbial transformation of immunosuppressive compounds. IV. Hydroxylation and hemiketal formation of ascomycin (immunomycin) by Streptomyces sp. MA 6970 (ATCC No. 55281)

J Antibiot (Tokyo). 1994 Dec;47(12):1557-9. doi: 10.7164/antibiotics.47.1557.
No abstract available

MeSH terms

  • Biotransformation
  • Fermentation
  • Hydroxylation
  • Immunosuppressive Agents / chemistry
  • Immunosuppressive Agents / metabolism*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Streptomyces / metabolism*
  • Tacrolimus / analogs & derivatives*
  • Tacrolimus / chemistry
  • Tacrolimus / metabolism

Substances

  • Immunosuppressive Agents
  • immunomycin
  • Tacrolimus