Interleukin-6: effects on tumor models in mice and on the cellular regulation of transcription factor IRF-1

Ann N Y Acad Sci. 1995 Jul 21:762:342-55; discussion 355-6. doi: 10.1111/j.1749-6632.1995.tb32338.x.

Authors

M Revel¹, A Katz, L Eisenbach, M Feldman, N Haran-Ghera, S Harroch, J Chebath

Affiliation

¹ Department of Molecular Genetics and Virology, Weizmann Institute of Science, Rehovot, Israel.

PMID: 7545371
DOI: 10.1111/j.1749-6632.1995.tb32338.x

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Base Sequence
DNA-Binding Proteins / metabolism
DNA-Binding Proteins / physiology*
Enhancer Elements, Genetic
Gene Expression Regulation, Neoplastic / drug effects*
Interferon Regulatory Factor-1
Interferon Regulatory Factor-2
Interferons / pharmacology
Interleukin-6 / pharmacology*
Interleukin-6 / therapeutic use
Leukemia, Myeloid, Acute / pathology
Leukemia, Myeloid, Acute / physiopathology
Melanoma, Experimental / physiopathology
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Neoplasm Metastasis
Phosphoproteins / physiology*
Regulatory Sequences, Nucleic Acid
Repressor Proteins*
Transcription Factors*

Substances

DNA-Binding Proteins
Interferon Regulatory Factor-1
Interferon Regulatory Factor-2
Interleukin-6
Irf1 protein, mouse
Irf2 protein, mouse
Phosphoproteins
Repressor Proteins
Transcription Factors
Interferons