Abstract
During their development and after their functional activation most lymphocytes die, either because they fail to receive a survival signal or because they are actively killed. Recent experiments on Bcl-2 and Fas/Apo-1 have provided evidence that these two death processes are subject to distinct genetic control.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Apoptosis / immunology*
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Cell Survival / immunology*
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Humans
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Proto-Oncogene Proteins / genetics*
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Proto-Oncogene Proteins c-bcl-2
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fas Receptor / genetics*
Substances
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-bcl-2
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fas Receptor