In vitro release of ketoprofren and ibuprofen from viscoelastic gels

Boll Chim Farm. 1995 Jun;134(6):312-5.

Abstract

Gels of viscoelastic type formed by isopropylmyristate, Tween 60 and water are prepared in the presence or not of antiinflammatory agents such as Ketoprofen and Ibuprofen. In vitro release studies evaluated by using an absorption simulator were performed in order to determine the diffusion rate of these drugs from prepared gels. The obtained results showed a higher rate diffusion compared with the release from commercial products containing these drugs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Elasticity
  • Excipients
  • Gels
  • Ibuprofen / administration & dosage*
  • Ibuprofen / chemistry
  • Ketoprofen / administration & dosage*
  • Ketoprofen / chemistry
  • Viscosity

Substances

  • Excipients
  • Gels
  • Ketoprofen
  • Ibuprofen