Fluorouracil: active in ZD1694 (tomudex)-resistant cell lines with markedly elevated thymidylate synthase levels

J Natl Cancer Inst. 1995 Oct 18;87(20):1558-9. doi: 10.1093/jnci/87.20.1558-a.
No abstract available

Publication types

  • Letter

MeSH terms

  • Drug Resistance
  • Fluorouracil / pharmacology*
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / enzymology*
  • Neoplasms / physiopathology
  • Quinazolines / pharmacology*
  • Thiophenes / pharmacology*
  • Thymidylate Synthase / analysis
  • Thymidylate Synthase / antagonists & inhibitors*
  • Tumor Cells, Cultured

Substances

  • Quinazolines
  • Thiophenes
  • Thymidylate Synthase
  • raltitrexed
  • Fluorouracil