Abstract
Primary bone non Hodgkin's lymphomas (PBL) are approximately 5% of extranodal lymphomas and 5% of all primary bone tumors. A standard treatment has not been codified yet. The most received only radiotherapy but recently it was introduced combined modality treatment with radiotherapy plus chemotherapy or chemotherapy alone. The authors describe two cases of high grade PBL that received combined treatment with chemotherapy (VACOP-B regimen and monochemotherapy with mitoxantrone respectively) and radiotherapy. The patients achieved complete remission and up to day are alive and disease free at 33 and 15 months from the diagnosis respectively.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Aged
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Antineoplastic Agents / therapeutic use
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bleomycin / therapeutic use
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Bone Neoplasms* / diagnosis
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Bone Neoplasms* / therapy
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Cobalt Radioisotopes / therapeutic use
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Combined Modality Therapy
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Cyclophosphamide / therapeutic use
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Doxorubicin / therapeutic use
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Etoposide / therapeutic use
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Follow-Up Studies
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Humans
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Humerus*
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Lymphoma, B-Cell* / diagnosis
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Lymphoma, B-Cell* / therapy
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Male
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Middle Aged
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Mitoxantrone / therapeutic use
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Prednisone / therapeutic use
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Radiotherapy Dosage
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Time Factors
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Vincristine / therapeutic use
Substances
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Antineoplastic Agents
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Cobalt Radioisotopes
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Bleomycin
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Vincristine
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Etoposide
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Doxorubicin
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Cyclophosphamide
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Mitoxantrone
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Prednisone