Abstract
The synthesis of a series of 2-aminobenzimidazole and indole amide derivatives containing the adamantyl moiety is described. The compounds, evaluated for in vitro anti-HIV and antitumor activities, were found to be moderately active or inactive, versus drug-treated controls, used for comparison purposes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adamantane / analogs & derivatives*
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Adamantane / chemistry
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Adamantane / pharmacology
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / pharmacology
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Antiviral Agents / chemistry*
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Antiviral Agents / pharmacology
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Benzimidazoles / chemistry*
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Benzimidazoles / pharmacology
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Cell Line
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Drug Evaluation, Preclinical
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Drug Screening Assays, Antitumor
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HIV / drug effects*
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Humans
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Molecular Structure
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents
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Antiviral Agents
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Benzimidazoles
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2-aminobenzimidazole
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Adamantane