Abstract
Clinicomorphological examination covered 100 patients with confirmed SLE: 79 with concomitant APS (group 1), 21 free of APS (group 2). In group 1 thrombolytic complications occurred in 75%, in group 2- in 13%. The recurrences were more frequent in group 1. Overall percentage of arterial and venous thromboses was approximately the same. According to biopsy and autopsy 2 kinds of morphological changes were found: typical for SLE and APS. Morphological specificity of APS manifested with proliferative and thrombotic changes in both arteries and veins.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Adolescent
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Adult
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Antiphospholipid Syndrome / complications*
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Antiphospholipid Syndrome / diagnosis
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Antiphospholipid Syndrome / pathology
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Autoimmune Diseases / complications*
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Autoimmune Diseases / diagnosis
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Autoimmune Diseases / pathology
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Biopsy
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Chronic Disease
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Female
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Humans
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Kidney / pathology
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Lupus Erythematosus, Systemic / complications*
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Lupus Erythematosus, Systemic / diagnosis
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Lupus Erythematosus, Systemic / pathology
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Male
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Middle Aged
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Muscles / pathology
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Skin / pathology
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Thrombosis / diagnosis
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Thrombosis / etiology*
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Thrombosis / pathology