Aim of the study is to detect a reperfusion injury in rat liver transplantation by the Ion-selective Surface-Measurement (OMS).
Methods: Lewis rats served as models for 30 liver transplantations with 1, 6 or 12 hrs of cold ischemia respectively. Directly before, during and after transplantation potassium- and hydrogen-concentrations were measured with the OMS and compared to transaminase values on day 1, 3 and 7 as well as to biopsies on day 3.
Results: Transaminase values and histology show ischemic cell injuries correlating to the length of ischemia, whereas potassium- and hydrogen-concentrations on the organ surface do not.
Conclusions: Ischemic cell injury in the rat liver cannot be detected by the Ion-selective Measurement.