Dextrocardia and situs inversus totalis is a rare congenital anomaly in adults. Usually, the patients have structurally normal hearts and experience normal longevity. The risk of coronary atherosclerosis is similar to that of the general population. However, the report of coronary angioplasty and/or coronary arteriography on patients with dextrocardia is scant. We describe herein a case of successful percutaneous transluminal coronary angioplasty to the right coronary artery. We comment the technical particularities of the procedure, and a review of the literature is made.