Immunoelectron microscopic study of HTLV-II-producing cells with an anti-envelope gp46 monoclonal antibody

N Ohara; K Hayashi; K Miyamoto; K Takahashi; Y Ohtsuki; T Akagi

doi:10.1007/BF01322755

Immunoelectron microscopic study of HTLV-II-producing cells with an anti-envelope gp46 monoclonal antibody

Arch Virol. 1995;140(7):1291-5. doi: 10.1007/BF01322755.

Authors

N Ohara¹, K Hayashi, K Miyamoto, K Takahashi, Y Ohtsuki, T Akagi

Affiliation

¹ Second Department of Pathology, Okayama University Medical School, Japan.

PMID: 7646360
DOI: 10.1007/BF01322755

Abstract

We observed expression of envelope gp46 protein on an HTLV-II-producing T-cell line (Mo) cells by an immunoelectron microscopical method using a monoclonal antibody against HTLV-II gp46. gp46 reactivity was observed on virus-like particles, extracellular vesicles, cell membrane, and partially in nuclear membrane and endoplasmic reticulum.

MeSH terms

Animals
Antibodies, Monoclonal / immunology
Antibodies, Viral / immunology
Cell Line
Gene Products, env / analysis*
Gene Products, env / immunology
Gene Products, env / metabolism
Gene Products, env / ultrastructure
Human T-lymphotropic virus 2 / immunology
Human T-lymphotropic virus 2 / metabolism
Human T-lymphotropic virus 2 / ultrastructure*
Humans
Mice
Microscopy, Immunoelectron
Retroviridae Proteins, Oncogenic / analysis*
Retroviridae Proteins, Oncogenic / immunology
Retroviridae Proteins, Oncogenic / metabolism
Retroviridae Proteins, Oncogenic / ultrastructure
T-Lymphocytes / cytology
Virion / immunology
Virion / metabolism
env Gene Products, Human Immunodeficiency Virus

Substances

Antibodies, Monoclonal
Antibodies, Viral
Gene Products, env
Retroviridae Proteins, Oncogenic
env Gene Products, Human Immunodeficiency Virus
gp46 protein, Human immunodeficiency virus 2