[Aspergillosis of the larynx]

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1995;30(2):111-3.
[Article in Chinese]

Abstract

Aspergillosis of the larynx is extremely rare. Six cases of aspergillosis of the larynx were presented. Clinical characters of the patients were as follows: (1) their physical conditions were excellent: (2) Hoarsenes was the first symptom; (3) true vocal cord demonstrated white mass; (4) Biopsy of the lesion revealed suppurative, granulomatous and necrotic inflammation with hyphae and spore with in the tissue; (5) Culture of fungi displayed tobaco colour colonies of aspergillus. microscopic examination demonstrated spore and septate hyphae with coral-shape dichotomous banching and flask-shape vesicle with phialide and spore on top; (6) All patients were cured with Ketoconazol and Itraconazol without recurrence for long-term follow-up. Etiology, diagnosis and therapy of aspergillosis of the larynx were discussed.

MeSH terms

  • Adult
  • Aspergillosis / drug therapy*
  • Aspergillus fumigatus* / isolation & purification
  • Female
  • Follow-Up Studies
  • Humans
  • Itraconazole / therapeutic use
  • Ketoconazole / therapeutic use*
  • Laryngeal Diseases / drug therapy*
  • Laryngeal Diseases / microbiology*
  • Male

Substances

  • Itraconazole
  • Ketoconazole