The stimulatory effect of clonidine on locus coeruleus noradrenergic neurons through imidazoline receptors is modulated by excitatory amino acids

Ann N Y Acad Sci. 1995 Jul 12:763:501-5. doi: 10.1111/j.1749-6632.1995.tb32441.x.

Authors

J Pineda¹, J A Ruiz-Ortega, L Ugedo, J A García-Sevilla

Affiliation

¹ Department of Pharmacology, University of the Basque Country, Leioa, Bizkaia, Spain.

PMID: 7677365
DOI: 10.1111/j.1749-6632.1995.tb32441.x

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adrenergic alpha-Antagonists / pharmacology
Animals
Clonidine / pharmacology*
Excitatory Amino Acids / metabolism*
Fenclonine
Imidazoline Receptors
Locus Coeruleus / cytology
Locus Coeruleus / drug effects*
Locus Coeruleus / metabolism
Male
Methyltyrosines
Neurons / drug effects
Neurons / metabolism
Norepinephrine / metabolism*
Quinolines / pharmacology
Rats
Rats, Sprague-Dawley
Receptors, Drug / metabolism*
Reserpine / pharmacology
alpha-Methyltyrosine

Substances

Adrenergic alpha-Antagonists
Excitatory Amino Acids
Imidazoline Receptors
Methyltyrosines
Quinolines
Receptors, Drug
EEDQ
alpha-Methyltyrosine
Reserpine
Clonidine
Fenclonine
Norepinephrine