Abstract
We describe a 12-year-old black male who presented with cervical lymphadenopathy, hepatosplenomegaly of 3 months duration, and ataxia and incoordination of recent onset. Hodgkin's disease, stage IVB, was diagnosed. An MRI of the head demonstrated a nonenhancing, well-defined pontine lesion. The pontine lesion and the associated neurologic symptoms were consistent with central pontine myelinolysis. Treatment of Hodgkin's disease resulted in complete remission and complete disappearance of the pontine abnormality.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bleomycin / administration & dosage
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Child
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Dacarbazine / administration & dosage
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Demyelinating Diseases / etiology*
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Doxorubicin / administration & dosage
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Hodgkin Disease / complications*
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Hodgkin Disease / diagnosis
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Hodgkin Disease / drug therapy
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Humans
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Magnetic Resonance Imaging
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Male
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Mechlorethamine / administration & dosage
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Pons / diagnostic imaging
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Pons / pathology*
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Prednisone / administration & dosage
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Procarbazine / administration & dosage
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Remission Induction
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Tomography, X-Ray Computed
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Vinblastine
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Vincristine / administration & dosage
Substances
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Bleomycin
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Procarbazine
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Mechlorethamine
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Vincristine
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Vinblastine
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Dacarbazine
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Doxorubicin
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Prednisone
Supplementary concepts
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ABVD protocol
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MOPP protocol