Comparison of serological tests and bio-assay for malaria transmission blocking capacity in field sera

Parassitologia. 1993 Jul:35 Suppl:95-7.

Abstract

Competition ELISAs have been developed for natural transmission blocking antibodies. Approximately 50% of the sera blocking in the conventional mosquito feeding experiments, gave positive results in these competition ELISAs. Attempts to adapt competition ELISAs to a field application have been partly successful.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anopheles / parasitology
  • Antibodies, Protozoan / blood*
  • Antibodies, Protozoan / immunology
  • Antigens, Protozoan / immunology*
  • Antigens, Surface / immunology
  • Biological Assay*
  • Carrier State / blood*
  • Carrier State / immunology
  • Enzyme-Linked Immunosorbent Assay*
  • Epitopes / immunology
  • Humans
  • Insect Vectors / parasitology
  • Malaria, Falciparum / blood*
  • Malaria, Falciparum / transmission
  • Plasmodium falciparum / immunology*
  • Plasmodium falciparum / isolation & purification
  • Protozoan Proteins / immunology*

Substances

  • Antibodies, Protozoan
  • Antigens, Protozoan
  • Antigens, Surface
  • Epitopes
  • Protozoan Proteins