[The effect of hyperthermia (45 C) on lymphoid cell aggregation]

Biofizika. 1995 Jan-Feb;40(1):115-6.
[Article in Russian]

Abstract

Hyperthermia (45 degrees C) has found to decrease the rate of rat thymocytes as well as splenocytes aggregation induced by lectins (concanavalin A, wheat germ agglutinin) and sulphated polysaccharides (heparin, dextran sulphate-500) and to increase those induced by cationic dye alcian blue. Shedding of plasma membrane glycoproteins and changes of surface charge are supposed to affect the aggregation.

Publication types

  • English Abstract

MeSH terms

  • Alcian Blue / pharmacology
  • Animals
  • Cell Aggregation / drug effects
  • Concanavalin A / pharmacology
  • Dextran Sulfate / pharmacology
  • Heparin / pharmacology
  • Hyperthermia, Induced*
  • Membrane Glycoproteins / metabolism
  • Rats
  • Spleen / drug effects
  • Spleen / metabolism
  • Spleen / pathology*
  • Thymus Gland / drug effects
  • Thymus Gland / metabolism
  • Thymus Gland / pathology*
  • Wheat Germ Agglutinins / pharmacology

Substances

  • Membrane Glycoproteins
  • Wheat Germ Agglutinins
  • Concanavalin A
  • Heparin
  • Dextran Sulfate
  • Alcian Blue