Intersubunit disulfide bonds in the molecule of baker's yeast transketolase

O N Solovjeva; Filippov MYu; G A Kochetov

Intersubunit disulfide bonds in the molecule of baker's yeast transketolase

Biochem Mol Biol Int. 1994 Nov;34(5):1049-54.

Authors

O N Solovjeva¹, Filippov MYu, G A Kochetov

Affiliation

¹ A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia.

PMID: 7703900

Abstract

It has previously been shown that baker's yeast trans ketolase has no intersubunit disulfide bonds and is able to dissociate reversibly into subunits at a low apoprotein concentration in solution. By contrast, in the present work it was found that in the molecule of transketolase C (a newly discovered form of the enzyme) subunits are bound to each other by disulfide bonds.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Disulfides / chemistry*
Protein Binding
Protein Conformation
Saccharomyces cerevisiae / enzymology*
Structure-Activity Relationship
Transketolase / chemistry*

Substances

Disulfides
Transketolase