Current management of meningiomas

Oncology (Williston Park). 1995 Jan;9(1):83-91, 96; discussion 96, 99-101.

Abstract

Although generally benign tumors, meningiomas can cause serious neurological injury and, at times, vexatious management difficulties. Currently, the accepted management of these tumors is attempted total surgical excision when technically possible and associated with an acceptable risk. However, even with innovations in instrumentation and refinements in surgical technique, the goal of total resection may not be achievable. For these patients, and for those with recurrent tumors, options for treatment include reoperation, radiation therapy, and chemotherapy. Recent developments in surgical technique and instrumentation, radiosurgery, and brachytherapy have increased the treatment options, while clinical trials with tamoxifen and mifepristone (RU486) are adding information on the effectiveness of these drugs as chemotherapeutic agents. While the search continues for a uniformly successful management plan, physicians must be aware of the available options and try to help the patient decide which treatment is appropriate, based on current medical knowledge.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Meningeal Neoplasms / complications
  • Meningeal Neoplasms / diagnosis
  • Meningeal Neoplasms / epidemiology
  • Meningeal Neoplasms / therapy*
  • Meningioma / complications
  • Meningioma / diagnosis
  • Meningioma / epidemiology
  • Meningioma / therapy*
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Neurosurgery / methods
  • Radiosurgery