New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. IV. Structural elucidation of novel isocoumarin derivatives

J Antibiot (Tokyo). 1995 Mar;48(3):267-70. doi: 10.7164/antibiotics.48.267.

Abstract

The structures of four new biologically active halogenated dihydroiso coumarins isolated from submerged cultures of the ascomycete Lachnum papyraceum have been elucidated by spectroscopic methods. The compounds are structurally related to lachnumon and mycorrhizin A, which are also produced by the fungus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemistry*
  • Antinematodal Agents / chemistry*
  • Ascomycota / chemistry*
  • Coumarins / chemistry*
  • Magnetic Resonance Spectroscopy
  • Structure-Activity Relationship

Substances

  • Anti-Infective Agents
  • Antinematodal Agents
  • Coumarins
  • mycorrhizin A