Abstract
During a one year prospective study of Haemophilus influenzae infections in patients treated in hospitals in the metropolitan area of Cape Town. H. influenzae type b accounted for 81.7% of 126 invasive isolates, whereas 86.1% of the 280 non-invasive isolates were non-typeable. Ampicillin resistance was detected among 10.8% of strains of which all but one produced beta-lactamase. All strains were susceptible to cefotaxime as were more than 95% to chloramphenicol, rifampicin, tetracycline but 20.4% were resistant to co-trimoxazole and 87.2% to erythromycin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Arthritis / microbiology
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Cefotaxime / pharmacology
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Cellulitis / microbiology
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Child
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Child, Preschool
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Drug Resistance, Microbial
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Erythromycin / pharmacology
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Haemophilus Infections / epidemiology
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Haemophilus influenzae / classification*
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Haemophilus influenzae / drug effects*
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Haemophilus influenzae / enzymology
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Humans
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Meningitis / microbiology
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Microbial Sensitivity Tests
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Pneumonia / microbiology
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Respiratory System / microbiology
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Serotyping
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South Africa / epidemiology
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beta-Lactamases / metabolism
Substances
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Erythromycin
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beta-Lactamases
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Cefotaxime