Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine

J Med Chem. 1995 May 12;38(10):1579-81. doi: 10.1021/jm00010a001.
No abstract available

MeSH terms

  • Adrenergic alpha-1 Receptor Antagonists
  • Adrenergic alpha-Antagonists / chemical synthesis*
  • Adrenergic alpha-Antagonists / pharmacology
  • Calcium Channel Blockers / chemistry*
  • Cell Line
  • Cloning, Molecular
  • Dihydropyridines / chemistry*
  • Humans
  • Receptors, Adrenergic, alpha-1 / genetics

Substances

  • Adrenergic alpha-1 Receptor Antagonists
  • Adrenergic alpha-Antagonists
  • Calcium Channel Blockers
  • Dihydropyridines
  • Receptors, Adrenergic, alpha-1
  • niguldipine