Opportunistic nosocomial multiply resistant bacterial infections--their treatment and prevention

J Antimicrob Chemother. 1993 Jul:32 Suppl A:39-47. doi: 10.1093/jac/32.suppl_a.39.

Abstract

One of the most difficult problems confronting the clinician who deals with nosocomial infections is that of microbial resistance. The predominant nosocomial infections (urinary tract infections, pneumonia, septicaemia, surgical wound infections) involve increasing numbers of Gram-positive bacteria, Staphylococcus epidermidis, Corynebacterium jeikeium or resistant enterococci as well as new multiresistant Gram-negative bacilli such as Xanthomonas maltophilia, Acinetobacter baumannii and Alcaligenes xylosoxydans. The emergence and spread of Klebsiella pneumoniae and other Enterobacteriaceae producing novel plasmid-mediated beta-lactamases active against third-generation cephalosporins contribute to the difficulty in treating nosocomial infections.

Publication types

  • Review

MeSH terms

  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • Cross Infection / prevention & control
  • Drug Resistance, Microbial
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / microbiology*
  • Gram-Negative Bacterial Infections / prevention & control
  • Gram-Positive Bacterial Infections / drug therapy
  • Gram-Positive Bacterial Infections / microbiology*
  • Gram-Positive Bacterial Infections / prevention & control
  • Humans
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / microbiology*
  • Opportunistic Infections / prevention & control
  • Pneumonia / drug therapy
  • Pneumonia / microbiology
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / microbiology
  • Wound Infection / drug therapy
  • Wound Infection / microbiology