Characterization of the C alpha-dehydrogenase gene involved in the cleavage of beta-aryl ether by Pseudomonas paucimobilis

Biosci Biotechnol Biochem. 1993 Oct;57(10):1655-9. doi: 10.1271/bbb.57.1655.

Abstract

C alpha-dehydrogenase catalyzes the oxidation of arylglycerol-beta-aryl ether at the C alpha-position, and therefore this process produces the specific substrate for beta-etherase, which cleaves beta-ary ethers (C alpha carbonyl type). Here we isolated the C alpha-dehydrogenase gene (lig D) and sequenced its nucleotides. This gene contains an open reading frame of 915 bp and the deduced amino acid sequence had a homology with the ribitol dehydrogenase family. lig D is about 1 kbp upstream of the beta-etherase gene (lig E).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohol Oxidoreductases / chemistry
  • Alcohol Oxidoreductases / genetics*
  • Alcohol Oxidoreductases / metabolism
  • Amino Acid Sequence
  • Bacterial Proteins*
  • Base Sequence
  • Blotting, Southern
  • Catalysis
  • Cloning, Molecular
  • Genes, Bacterial
  • Lignin / metabolism*
  • Molecular Sequence Data
  • Oxidation-Reduction
  • Oxidoreductases / chemistry
  • Oxidoreductases / genetics*
  • Oxidoreductases / metabolism
  • Pseudomonas / enzymology*
  • Pseudomonas / genetics
  • Restriction Mapping
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Substrate Specificity

Substances

  • Bacterial Proteins
  • Lignin
  • Oxidoreductases
  • aryl ether cleaving enzyme
  • Alcohol Oxidoreductases
  • Calpha-dehydrogenase